Regular cannabis use as a risk factor for schizophrenia accounted for 7,000 DALYs (3,000-13,000) or 0.04% (0.03-0.06%) of schizophrenia DALYs globally (Table 3). Overall, North America, high income was the region with highest number of attributable DALYs (2,000 DALYs). Males were responsible for over twice as many attributable schizophrenia DALYs (5,000 DALYs; 2,000-10,000) than females (2,000; 1,000-4,000); and attributable DALYs peaked between 25 and 30 years and decreased thereafter. When the additional burden attributable to cannabis use as a risk factor for schizophrenia was added to that of cannabis dependence, cannabis use still accounted for 0.08% of global DALYs in 2010.