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Chunk #16 — DISCUSSION

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Blood glucose level, alcohol heavy drinking, and alcohol craving during treatment for alcohol dependence: results from the Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence (COMBINE) Study.
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As a consequence, our finding further supports the value of medical interventions aimed at achieving alcohol abstinence or at least a significant reduction of alcohol consumption in heavy drinkers. In keeping with this medical need, it has been demonstrated that three months of total alcohol abstinence leads to reductions in both blood glucose level and consequently, the risk of developing metabolic and cardiovascular disorders (Addolorato et al., 1998).