the treatment in the column and values below 1 favour the treatment in the row. Results in bold are significant. Drugs are reported in alphabetical order. Results are based on network estimates. No data for clonidine and guanfacine in adults are reported because no studies identified by our search tested these two drugs in adults. ADHD=attention-deficit hyperactivity disorder.*Low quality of evidence.†Very low quality of evidence.‡Moderate quality of evidence.§High quality of evidence.