more liberal p value inclusion thresholds) as construction of allelic scores in ALSPAC was based on the much larger Teslovich et al meta-analysis. Although the proportion of variance explained in ALSPAC was greater than that found by Demirkan et al., we note that the pattern of variance explained across the different SNP inclusion thresholds was similar across both studies as well as the QIMR replication set (i.e. as the threshold becomes less stringent, less variance is explained).
