Chunk #77 — Results — Detecting recombination events — Informative pedigrees

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A general approach for haplotype phasing across the full spectrum of relatedness.

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These results on both simulated and real data point to elevated false discovery rates for recombination detection with Merlin, corroborating what has previously been reported in the literature [39] whereas the SHAPEIT2+duoHMM method can constrain FDR whilst still detecting a substantial proportion of true crossover events.