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Chunk #32 — Discussion — Frontal alpha hypoconnectivity

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Altered resting-state EEG source functional connectivity in schizophrenia: the effect of illness duration.
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FC, more pronounced in the left hemisphere (Peng et al., 2013). Finally, an alpha band decrease from resting-state EEG-SFC was recently shown in first episode, drug-naïve SCZ (Lehmann et al., 2014). Due to the key role of alpha oscillations as neural substrates of attention modulation through the suppression/inhibition and selection functions (Klimesch, 2012), impairment in alpha resting-state connectivity might be one of the main indices of long lasting and stable cognitive deficit observed in SCZ.