Chunk #26 — Candidate Gene Association Studies for Alcohol and Nicotine Dependence — Other Candidate Genes — Genes Potentially Associated with Multiple Disorders
Other genes involved in important nerve cell signaling pathways, such as those using the neurotransmitters acetylcholine, dopamine, serotonin, and endogenous opioids, have been found to be associated with alcohol dependence, nicotine dependence, or both (for reviews see Dick and Foroud 2003; Tyndale 2003; Dick and Bierut 2006; Li 2006). For example, several different types of nicotinic receptors have been implicated in the development of nicotine dependence (Li 2006). Because these receptors serve a number of important neurobiologic functions, they constitute candidate genes for other disorders as well.
