The Irish Affected Sib Pair Study of Alcohol Dependence (IASPSAD) sample (Prescott et al., 2005) included alcoholic probands recruited from hospitals and community alcohol treatment facilities in Ireland and Northern Ireland. Eligible probands of European ancestry underwent a clinical interview for AUDs and provided information on potentially affected siblings, who were also assessed with a clinical interview. This sample included 591 probands and 610 affected siblings, all of whom met DSM-IV criteria for an alcohol dependence diagnosis. Phenotypic and genotypic data were available for a subset of this sample, resulting in a total of 706 participants from 430 families (34.3% female; M age = 41.8, range = 17 – 71) included in the present analyses.
