cases and controls were matched by sex, age, RINs, and postmortem intervals (PMIs). Characteristics (including the amount of daily alcohol use, sex, age, PMIs, RINs, brain weight, brain pH, cerebral hemispheres, smoking, and liver disease) of these two sets of RNA samples chosen for transcriptome analysis are summarized in Table S1. Except the amount of daily alcohol consumption, other demographic variables were not significantly different in their measurements (or counts) between cases and controls.