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Chunk #11 — Results — Putative functional polymorphisms

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Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.
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All other SNPs implicated for FEV1/FVC or FEV1 are intergenic, intronic, or located in 3’ untranslated regions. Of these, three intronic GPR126 SNPs (rs9496346, rs1040525, and rs6929442) and one intergenic SNP near NPNT (rs10516529) are located in transcription factor binding sites, according to the UCSC genome browser15.