Shown in Table 4 are the standardized path coefficients for A, C and E influences on AUD and on remission (contingent on history of AUD) for saturated and best-fitting models (see Supplementary Tables S1 and S2 for fit statistics). Familial influences on remission were small to moderate, with all familial effects in males attributable to shared environment (C; accounting for 37% of the total variance), and all familial effects in women attributable to genetic factors (A; accounting for 11% of the total variance). The negative path coefficients for influences common to AUD and remission suggest that environmental (in males and females) and genetic influences (in females) associated with AUD inhibit the likelihood of remission.
