Researchers await the results of other studies that may confirm these findings. However, replication of linkage findings in complex disorders such as alcoholism and depression is likely to be difficult (Suarez et al. 1994). In disorders to which multiple genetic factors contribute but for which no single factor is absolutely necessary, evidence for specific effects can differ among different data sets (i.e., for different study samples). Accordingly, the replication of any given effect may require several studies with data sets of a size equivalent to the original data set.