Seventh, we have quantified the attributable burden of risk factors, holding all other independent factors constant. For clusters of risk factors we have approximated the joint effects, assuming that risk factors within each cluster are independent. A more accurate quantification of the joint effects of multiple risk factors is an important area for future research. Finally, it is important to stress that the size of the attributable risk factor burden does not equal priority for action since prioritisation also depends on availability, cost, and effectiveness of inter vention strategies to reduce exposures to these risks.