The 2,108 mRNA transcripts and 390 proteins with differential expression between lines (FDR and p<0.05, respectively) were submitted to PaintOmics3 for an integrated KEGG pathway enrichment analysis (Hernández-de-Diego et al. 2018). The combined pathway analysis did not reveal any pathways significantly enriched for the combined datasets; however, images of genes/proteins that were differentially expressed in the present study were mapped onto the glutamatergic synapse and GABAergic synapse KEGG pathways as these pathways are of relevance to our previous work and may be of interest to the reader (Supplemental Figure 4).
