The LD block of PHF3-PTP4A1 containing the association signals overlapped extensively across AAs, EAs and Australians ( Figure 1B and 1C ; Table 2 ). The LD block that was enriched with functional signals across HapMap CEU-Children, CEU-Parent and CHB populations overlapped extensively with the region that had significant association signals across AAs, EAs and Australians ( Figure 1B–C and 1D–F ). The distributions of −log(p) values for association and functional signals across AA, EA, Australians, CHB and CEU-Children populations were highly consistent (Pearson correlation coefficient r≥0.465 with 2.5×10−21≤p≤4.0×10−4), and were negatively correlated with that in YRI-Children (r≤−0.407; 5.7×10−6≤p≤9.2×10−4; Table 2 and Figure 1 ).
