We also examined whether adolescents with a lifetime history of substance use reported a greater prevalence of parental problematic substance use than youth who had never used substances. As evident in Table 2, female adolescents with a lifetime history of alcohol, cigarettes, and prescription drug use reported a greater prevalence of maternal problematic substance use than adolescents who had never used these substances. Further, females with a lifetime history of alcohol, cigarettes, marijuana, ecstasy, and prescription drug use reported a higher prevalence of paternal problematic use than females who had never used these substances. For males, adolescents with a lifetime history of cigarettes, marijuana, ecstasy, and prescription drug use reported a greater prevalence of maternal problematic substance use than those who had never used these substances. Moreover, males with a lifetime history of alcohol, cigarettes, marijuana, ecstasy, and prescription drug use reported a higher prevalence of paternal problematic use than males without lifetime use of these substances.