the endogenous coupling of ipsilesional SMA and M1, and with a significant decrease of the pathologic inhibition from contralesional M1 to ipsilesional M1 with movement of the paretic hand. The magnitude of the reduction in this pathologic inhibition was correlated with the degree of improvement in motor performance of the paretic hand (Grefkes et al., 2010). Thus, this study demonstrated that rTMS might promote more efficient network interactions in both ipsilesional and contralesional cortex. The techniques utilized in this study hold significant potential for understanding how brain stimulation techniques affect cortical networks, and thus should enable the development of more effective therapeutic protocols.
