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Chunk #16 — Results — Working Memory

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Large-scale brain network coupling predicts acute nicotine abstinence effects on craving and cognitive function.
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We found significant RAI-task activation correlations in all task-negative but not task-positive regions. The decrease of the left hemisphere RAI during the abstinence state predicted less WM task-induced BOLD deactivation in the VMPFC (r = −0.66; P = .003) and PCC (r = −0.65; P = .001; Figure 5). No significant interactions of memory load by the RAI on performance or activation were found.