The change of the right hemisphere RAI (abstinence – smoking) was negatively correlated with changes in smoking urge (r = −0.59; P = .007). Compared with the smoking state, the more the right hemisphere RAI decreased during abstinence, the more urges the subject reported (Figure 4). The change in the right hemisphere RAI showed a trend for a similar negative correlation (r = −0.35; P = .09) with withdrawal changes measured by the Minnesota Nicotine Withdrawal Scale. The increase in negative affect showed a nonsignificant negative correlation with RAI change (r = −0.37; P = .09).