The RAI combined SN-ECN and SN-DMN coupling. To better understand which between-network connection was responsible for reducing the RAI during abstinence, we performed post hoc analyses on the session effects of the SN-ECNcoupling(zSN,LECN andzSN,RECN)and the SN-DMN coupling (zSN,DMN), controlling for all the above covariates. The anticorrelation between the SN and DMN was significantly reduced during the abstinence state(P = .02),where as the correlation between the SN and LECN(P = .04)but not the correlation between the SN and RECN (P = .45) was reduced (Figure 3).