Chunk #45 — Discussion

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The effect of alcohol on the differential expression of cluster of differentiation 14 gene, associated pathways, and genetic network.

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Among the 20 genes identified in the network, five of them (Tlr2, Il18, Cst3, Csf3, and Smpd1) are significantly correlated with alcohol exposure based on literature reports. Thus, they may interact with Cd14 to regulate ethanol responses.