Chunk #236 — VIII. A possible underlying neurobiology: connectivity constellations — B. Quality and/or quantity of connections involved in vulnerabilities
illnesses with almost 19 billion in such costs, developmental disorders with perhaps 5 billion in such costs and stroke, Parkinson’s disease, multiple sclerosis and seizures with 2, 1.4, almost 3 and 0.6 billion, respectively, that can be attributed to complex genetics. If variants in the “connectivity constellation” of genes contribute 20% to the complex genetic impact of these disorders, then the costs attributable to these cell adhesion related gene variants could amount to almost 90 billion in the US annually.
