Table 3 displays estimated genetic correlations between AD and several immune mediated diseases recorded in LD Hub. As expected, the estimated genetic correlation (rG) between AD and asthma was strongly significant and positive. We also note that the rG between AD and Crohn’s disease was moderate, significant and positive, perhaps reflecting substantial overlap between currently known loci for both conditions (Paternoster et al., 2015). rG did not differ significantly from zero for the other traits, although the point estimates for several were moderate indicating that follow up when larger samples become available may be justified. Table 3Genetic correlation between atopic dermatitis and other immune mediated diseasesTraitsrGSE_rGP_rGCrohn's disease0.180.090.03Ulcerative colitis0.100.100.31Asthma0.550.150.0002Rheumatoid Arthritis−0.070.080.40rG refers to the genetic correlation between two traits, SE_rG is the standard error of the genetic correlation, P_rG is the p value of the genetic correlation.
