Chunk #4 — Materials and Methods — Study subjects

Source

Variants located upstream of CHRNB4 on chromosome 15q25.1 are associated with age at onset of daily smoking and habitual smoking.

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yes

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The Human Studies Committee at the Washington University School of Medicine in Saint Louis approved the study. Approval number for our Collaborative Study on Genetics of Alcoholism: Molecular Biology of Alcoholism is 04-0057. A written informed consent was reviewed and obtained from family members.