In multivariable analyses, MMT discontinuation was positively associated with recent homelessness (Adjusted Odds Ratio [AOR] = 1.46, 95% CI: 1.09–1.95), daily heroin injection (AOR = 5.17, 95% CI: 3.82–6.99), daily prescription opioid use (AOR = 2.18, 95% CI:1.30–3.67), recent incarceration (AOR = 1.46, 95% CI: 1.01–2.12), and not being on any form of income assistance (AOR = 2.14, 95% CI: 1.33–3.46). MMT discontinuation was negatively associated with having a greater proportion of consecutive follow-ups on MMT (AOR = 0.63, 95% CI: 0.47–0.85) and being on methadone dose >100 mg per day (vs. ≤60 mg per day) at the most recent follow-up visit (AOR = 0.44, 95% CI: 0.31–0.62).
