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Chunk #14 — Methods — Genetic Analyses — Quality Control (QC)

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Examining the role of common genetic variants on alcohol, tobacco, cannabis and illicit drug dependence: genetics of vulnerability to drug dependence.
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For all genetic analyses, we retained 796,125 autosomal markers with an allele frequency > 1%, a call rate ≥ 99%, and a Hardy–Weinberg Equilibrium (HWE) p-value greater than 0.0001 among subjects of European descent.