Chunk #51 — Methods — Analysis of other phenotypes

Source

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.

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yes

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We also employed MAGMA on the summary statistics of these additional phenotypes to examine whether the LoF-intolerant gene set enrichment displayed specificity to schizophrenia, after excluding the xMHC and APOE regions.