Using ES twin families, Herndon and Iacono (2005) extended our earlier MTFS work demonstrating familial transmission of externalizing disorders (Hicks et al., 2004) by showing that parental antisociality is associated with increased risk for childhood disruptive disorders at age 11 and a wide range of externalizing disorders by age 17. Similar effects are evident for the offspring of parents with alcohol and illicit drug use disorders (Marmorstein et al., 2009). Personality profiles are also deviant in children with childhood disruptive disorders, with low constraint and high negative emotionality a common feature (Cukrowicz et al., 2006).
