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Chunk #29 — DISCUSSION

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Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.
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We show a novel genetic distinction between drinking in the pathological range (AD) and habitual drinking that does not cross the threshold into pathology or dependence nor captures behavioral aspects of disordered drinking. Larger future samples will allow us to uncover additional pleiotropy between pathological and non-pathological alcohol use as well as between AD and other neuropsychiatric disorders.