Chunk #6 — How do we define organoids and 3D cultures?

Source

Organoids: A historical perspective of thinking in three dimensions.

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(4) “Here we define an organoid as an in vitro 3D cellular cluster derived exclusively from primary tissue, embryonic stem cells, or induced pluripotent stem cells, capable of self-renewal and self-organization, and exhibiting similar organ functionality as the tissue of origin” (Fatehullah et al., 2016).