The list of ClinVar genes was downloaded from https://www.ncbi.nlm.nih.gov/clinvar/. TWAS results published in ref. 24 were used. Prediction model weights and covariances for different tissues are available from the predictdb.org resource. The results of MetaXcan applied to the 44 human tissues and a broad set of phenotypes can be queried in gene2pheno.org, and we make the full data set of results available via the public GitHub repository https://github.com/hakyimlab/MetaXcan.
