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Chunk #3 — METHODS — Genotyping and quality control procedures

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Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1.
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Genotyping for the replication sets was completed using the iPLEXtm Sequenom MassArray® platform. Included in each 96-well plate as QC samples were two negative controls (water), two blinded duplicates, and two samples included in the HapMap project. The mean concordance rate was 99.7% for blind duplicates (2,572 comparisons) and 99.2% for HapMap samples (1,751 comparisons).