Study inclusion criteria comprised (1) written in English language and peer-reviewed, (2) contains a statistical comparison of WM by means of VBM or DTI in the whole brain, (3) compares adult patients diagnosed with AUD (DSM-IV, DSM-5, or ICD-10) with healthy controls. AUD (as specified in DSM-5) is referred to as a disorder continuum subsuming DSM-IV diagnosis of alcohol abuse and alcohol dependence as well as ICD-10 diagnosis of harmful alcohol use and alcohol dependence. (4) Results were reported as 3D coordinates in a standard reference space.
