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Chunk #8 — 2 Methods and Materials — 2.2 Clinical variables

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Genetic and neurophysiological correlates of the age of onset of alcohol use disorders in adolescents and young adults.
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Diagnostic measures for outcomes were taken from direct interviews using the Semi Structured Assessment of Alcoholism (SSAGA) instrument (Bucholz et al., 1994; Hesselbrock et al., 1999). Data were obtained from child (CSSAGA-I, CSSAGA-II) and adult (SSAGA-IV) versions of the SSAGA. DSM-IV criteria were used for alcohol dependence and DSM-III-R criteria were used for other substance-use related diagnoses. Once the criteria for a diagnosis were met, the diagnosis was recorded as present, regardless of any subsequent change in status as determined by succeeding interviews. The age of onset was determined from data obtained at the first interview that recorded the diagnosis as present.