For EA participants, we calculated externalizing polygenic scores using estimates from the recent multivariate genomic analysis results of externalizing behaviors/ problems (including alcohol problems, ADHD, lifetime cannabis use, age of first sexual intercourse, number of sexual partners, general risk tolerance, and lifetime smoking initiation) with an effective sample size of ~1.5 million individuals of European ancestry, from the international Externalizing Consortium (Karlsson Linnér et al., 2021).
