Subjects orally rated subjective responses to the alcohol infusion on the “high” (operationally to subjects as, “up-stimulated, feeling good”) and “intoxicated” (“drunk, tipsy, inebriated”) items of the Subjective High Assessment Scale (SHAS; Schuckit et al., 2000). Before starting the infusion pump, subjects used a uniform baseline of zero, with ratings subsequently varying from the 0 baseline to a maximum of 100 (the most “high” or “intoxicated” ever). Ratings were obtained at baseline, after the calculated BrAC target before functional imaging, between each fMRI scan, and once after the last scan. After imaging, subjects left the scanner, and with the infusion pumps running a BrAC measurement was obtained.
