Chunk #27 — RESULTS — Reductions in responding for ethanol after GABAAR α4 subunit knockdown are present when testing occurs at the time of maximal knockdown and require ethanol reinforcement

Source

Alpha4 subunit-containing GABAA receptors in the accumbens shell contribute to the reinforcing effects of alcohol.

Embedded

yes

Text

There was no significant difference in inactive lever responding at any timepoint among all groups, both reinforced and non-reinforced (range: 0–6 per 30 minutes session among all groups).