Analyses were stratified by ancestry: European, Asian, and African American. We evaluated the effect of each bin A SNP using single SNP association analyses. For bins B, C, and D, both single SNP association and conditional analyses controlling for bin A were performed. Analyses conditional on bin A (rs16969968) served as our primary analysis model for bins B, C, and D because they were targeted due to previously reported results of analyses conditional on bin A in European ancestry meta-analyses.
