Chunk #15 — METHODS — Statistical Analyses and Meta-Analyses

Source

Smoking and genetic risk variation across populations of European, Asian, and African American ancestry--a meta-analysis of chromosome 15q25.

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For each ancestry group, every dataset with at least one genotyped SNP in a given sub-bin contributed to the meta-analysis of that sub-bin. For each sub-bin, a SNP was selected as the target. In samples where the target SNP was missing, we used the results from the SNP with highest correlation (r2) with the target SNP in the sub-bin defined by the 1000 Genome Pilot 1 JPT/CHB for Asians, and the 1000 Genome Pilot 1 YRI or HapMap3 ASW project for African Americans.