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Chunk #16 — METHODS — Statistical Analyses and Meta-Analyses

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Smoking and genetic risk variation across populations of European, Asian, and African American ancestry--a meta-analysis of chromosome 15q25.
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We used PLINK to perform meta-analyses and generate overall summary odds ratios (OR), standard errors, and p values [Purcell, et al. 2007]. The R package, rmeta, was used to confirm results and generate meta-analysis plots. Meta-analyses results were based on fixed effect models to determine the evidence for association within our collected samples, so we are not making a general inference about what might be observed in other samples.