Several variants were found to be clustered in the cardiomyopathy associated 3 gene CMYA3 in the African Americans. CYMA3, also known as XIRP2, the xin actin-binding repeat containing 2 gene, is primarily expressed in striated muscle. Another variant in CMYA3, rs3749004 (not in our study), has been reported to be associated with autism (Faham et al., 2005).
