The PFC performs several important functions in the brain. Unlike most previous fNIRS studies of brain network in resting-state, the present study used fOT to investigate the time-series and spectrum analysis of gender effect in the PFC during resting-state. In our study, although the quantitative correlation analysis shows strong linear connection of hemodynamic responses between male and female group (Fig. 4), the correlation matrices (Fig. 3) show that the male group possess higher connection of each paired channel than the female group in all hemodynamic responses. Besides, more noteworthy is that the fOT data of ΔHbO2, ΔHb and ΔtHb are higher in male group than in female group with the resting-state condition. Gender differences in brain function of PFC such as memories, sense emotions social sensitivity et al. have been reported by previous studies [25]. Although the behavioral function of resting-state network is still unclearly, it has been suggested that the resting-state brain network plays a role of associated with environmental stimuli as well as organizing processes such as reviewing past knowledge or preparing future actions [45]. Thus, our results
