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Chunk #21 — Discussion

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Depression and anxiety in relation to catechol-O-methyltransferase Val158Met genotype in the general population: the Nord-Trøndelag Health Study (HUNT).
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This is the first population-based study evaluating the relationship between HADS and the Val158Met polymorphism. In a group of 5,531 unselected adults, no significant association was found with anxiety and depression using the cut-off score ≥ 8 for HADS-A and HADS-D.