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Chunk #13 — Methods — FTO×PA Interaction Analysis in Participating Studies

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Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children.
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The interactions and associations of continuous outcome variables were analyzed with linear regression and those of dichotomous variables with logistic regression. In adults, BMI, waist circumference, and body fat percentage were analyzed as non-transformed variables, whereas in children, age- and sex-specific Z-scores of BMI, waist circumference, and body fat percentage were used.