All BrACs after the placebo session were zero (SD = 0) by design, while the mean value of BrAC following alcohol infusion, after removing subjects from the scanner, was 50 mg% (SD = 3.0). Figure 2 shows perceived “high” and “intoxication” ratings as a function of each of the sequential time points at which these measurements were made. A 2(Session) × (Time) repeated measures analysis of variance, with Session representing infusion type, and Time representing the 7 time points of measurement, showed no significant main effects for Session or Time on perceived “high” (p’s > 0.5), and no significant Session × Time interaction (p = 0.15; all p values reported using the Greenhouse-Geisser correction for observed violations of sphericity). A similar model for perceived “intoxication” also showed no significant main effects for Session or Time (p’s > 0.5), but a borderline Session × Time interaction (F = 3.94, p = 0.06 with Greenhouse-Geisser correction). Thus, as a whole, perceived “high” and “intoxication” were highly similar across both alcohol and placebo sessions, and reflected the relatively low level of brain exposure to alcohol that was employed.
