Analyses of individual disorder PRS and specific substance involvement revealed several noteworthy associations (see Figure 2; Supplementary Tables S2–S7 for all associations), some of which remained significant when controlling for general substance involvement (i.e., GENSUB; Supplementary Tables S2–S7). We report all nominally significant associations below and note which survived permutation-based correction for multiple comparisons within the text and in Supplementary Tables S2–S7.
