Chunk #52 — MATERIALS AND METHODS — QC and association testing — Quality control

Source

Novel common copy number variation for early onset extreme obesity on chromosome 11q11 identified by a genome-wide analysis.

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For QC of the CNVR-tagging SNP genotypes (at rs9804659 and rs2815752) in the replication sample of 365 case-parents obesity trios, an exact test for deviations from Hardy–Weinberg equilibrium (46) was performed in the set of parents (minimal two-sided exact P-value across both SNPs = 0.33).