We calculated four dichotomous FH scores, akin to those that have been extensively used in previous studies. The FH scores were calculated based on 1) The category of the family relative, which included father, mother, either parent, and any first-degree relative and 2) The affectedness criterion based on DSM-5 AUD lifetime diagnosis. Accordingly, for each subject, we computed four dichotomous FH scores: 1) Father with DSM-5 AUD diagnosis (FHFather–AUDDx), 2) Mother with DSM-5 AUD diagnosis (FHMother–AUDDx), 3) Either parent with DSM-5 AUD diagnosis (FHParent–AUDDx), and 4) Any first-degree relative with DSM-5 AUD diagnosis (FHFirst–AUDDx).
