In contrast to the findings with rs16969968, there was no evidence of an interaction between rs3743078 and parent monitoring (p=.80, see multivariate model 2 in Table 2 right panel). Because rs16969968 and rs3743078 are two evolutionarily related SNPs with distinct genetic effects (14), we tested this result and the interaction between lowest quartile parent monitoring and risk genotype of rs3743078 (CG/GG) while holding the rs16969968 genotype constant (GG) by conducting the same analyses in subjects with the same genotype for rs16969968 (GG). The interaction between rs578776 and parent monitoring was still not significant in the multivariate logistic regression model, even when another genetic risk factor rs16969968 was held constant (p=.60).
