Chunk #60 — Methods — Bias adjustment

Source

Adjustment for index event bias in genome-wide association studies of subsequent events.

Embedded

yes

Text

The bias-corrected effect on prognosis is \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\hat \beta _{GY} = \hat \beta _{GY}^\prime - \hat b\hat \beta _{GX}$$\end{document}β^GY=β^GY′-b^β^GX, with variance\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$var\left( {\hat \beta _{GY}^\prime } \right) + var\left( {\hat b\hat \beta _{GX}} \right)$$\end{document}varβ^GY′+varb^β^GX